Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31191672 | 0.92 | HDAC4 (0.41) | KDM1AHDAC4ALDH1A1SMN1; SMN2NPSR1 | |
| Formic Acid SCHEMBL31064289 | 0.86 | HDAC4 (0.38) | KDM1AHDAC4ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL31703464 | 0.77 | HDAC4 (0.44) | KDM1AHDAC4ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL31703382 | 0.75 | AKR1C3 (0.41) | BACE1HDAC4ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL28376946 | 0.75 | AKR1C3 (0.41) | BACE1HDAC4ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL31703956 | 0.69 | TSHR (0.60) | ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL16639029 | 0.66 | HDAC4 (0.71) | HDAC4ALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL6339509 | 0.66 | HDAC4 (0.71) | HDAC4ALDH1A1SMN1; SMN2HPGDLMNA | |
| (+)-Tranylcypromine SCHEMBL15541916 | 0.66 | MAOB (0.67) | KDM1AHPGDMAOBKDM4ELMNA | |
| SCHEMBL31191667 | 0.64 | GPR88 (0.35) | KDM1AALDH1A1KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215536-A1 | MACROCYCLIC PANRAS INHIBITORS FOR THE TREATMENT OF CANCER | NOVARTIS AG (CH) | 2025-10-16 | — | — | WO | disclosed |