Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31191672 | 0.94 | HDAC4 (0.41) | HDAC4ALDH1A1SMN1; SMN2NPSR1HPGD | |
| Trifluoroacetic Acid SCHEMBL31703769 | 0.86 | KDM1A (0.40) | HDAC4ALDH1A1SMN1; SMN2NPSR1HPGD | |
| SCHEMBL28376946 | 0.80 | AKR1C3 (0.41) | HDAC4ALDH1A1SMN1; SMN2NPSR1HPGD | |
| SCHEMBL31703382 | 0.80 | AKR1C3 (0.41) | HDAC4ALDH1A1SMN1; SMN2NPSR1HPGD | |
| SCHEMBL31703464 | 0.79 | HDAC4 (0.44) | HDAC4ALDH1A1SMN1; SMN2NPSR1HPGD | |
| SCHEMBL31703956 | 0.73 | TSHR (0.60) | ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL16639029 | 0.67 | HDAC4 (0.71) | HDAC4ALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL6339509 | 0.67 | HDAC4 (0.71) | HDAC4ALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL31703439 | 0.67 | SLC6A4 (0.40) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL31191667 | 0.66 | GPR88 (0.35) | ALDH1A1KDM1AKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676540-A1 | PANRAS INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | Novartis AG (CH) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024189481-A1 | PANRAS INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | NOVARTIS AG (CH) | 2024-09-19 | — | — | WO | disclosed |