Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.38 |
| ▸ | PDE4A | P27815 | 5/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31705706 | 1.00 | ACACB (0.46) | ACACBPOLBPDE4DPDE4APDE4B | |
| SCHEMBL797553 | 0.81 | MAPT (0.47) | ACACBPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL31704757 | 0.81 | ACACB (0.46) | ACACBPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL31704790 | 0.81 | ACACB (0.46) | ACACBPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL841376 | 0.79 | HCAR3 (0.45) | ACACBPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL17112460 | 0.78 | ATXN2 (0.43) | ACACBPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL29663877 | 0.78 | ATXN2 (0.43) | ACACBPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL26151979 | 0.78 | AKT1 (0.43) | ACACBLRRK2GRM5 | |
| SCHEMBL17112481 | 0.77 | ATXN2 (0.58) | ATXN2 | |
| SCHEMBL29950800 | 0.77 | ACACB (0.42) | ACACBPDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |