Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 14/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL31705741 | 0.89 | NAMPT (0.41) | NAMPTGAAALDH1A1TSHRKDM4E | |
| SCHEMBL31705649 | 0.88 | NAMPT (0.42) | NAMPTADAM10MMP2 | |
| SCHEMBL31706700 | 0.81 | NAMPT (0.43) | NAMPTGAAALDH1A1TSHRKDM4E | |
| SCHEMBL31705199 | 0.80 | NAMPT (0.41) | NAMPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL31706346 | 0.74 | NAMPT (0.42) | NAMPTGAAALDH1A1TSHRKDM4E | |
| SCHEMBL31706435 | 0.73 | ALDH1A1 (0.48) | NAMPTGAAALDH1A1TSHRKDM4E | |
| Lithium Ion SCHEMBL31705374 | 0.72 | NAMPT (0.42) | NAMPTGAAALDH1A1TSHRKDM4E | |
| Lithium Ion SCHEMBL31704850 | 0.72 | NAMPT (0.42) | NAMPTGAAALDH1A1TSHRKDM4E | |
| Lithium Ion SCHEMBL31705507 | 0.72 | NAMPT (0.30) | NAMPT | |
| SCHEMBL31705506 | 0.72 | JAK1 (0.45) | NAMPTGAAALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |