Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | JAK1 | P23458 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | QDPR | P09417 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31704732 | 0.90 | CCNT1 (0.44) | NAMPTALDH1A1SMN1; SMN2QDPRCCNT1 | |
| Lithium Ion SCHEMBL31705308 | 0.84 | ALDH1A1 (0.46) | NAMPTALDH1A1JAK1SMN1; SMN2JAK2 | |
| SCHEMBL31704953 | 0.81 | NAMPT (0.52) | NAMPTJAK1CCNT1CDK9 | |
| SCHEMBL31706191 | 0.81 | NAMPT (0.47) | NAMPTALDH1A1JAK1SMN1; SMN2JAK2 | |
| SCHEMBL31704895 | 0.81 | NAMPT (0.47) | NAMPTALDH1A1JAK1SMN1; SMN2JAK2 | |
| SCHEMBL31704700 | 0.79 | NAMPT (0.48) | NAMPTALDH1A1JAK1JAK2TYK2 | |
| SCHEMBL31705531 | 0.77 | CCNT1 (0.38) | ALDH1A1SMN1; SMN2CCNT1CDK9 | |
| SCHEMBL31706435 | 0.76 | ALDH1A1 (0.48) | NAMPTALDH1A1SMN1; SMN2ALOX15TSHR | |
| SCHEMBL31705266 | 0.75 | TLR8 (0.48) | ALDH1A1QDPR | |
| SCHEMBL31704981 | 0.74 | TDP1 (0.49) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |