Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.56 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 10/20 | 0.45 |
| ▸ | GRM5 | P41594 | 9/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31705807 | 1.00 | GPR119 (0.56) | GPR119JAK1GRM1GRM5PDK4 | |
| SCHEMBL20541569 | 0.89 | GPR119 (0.56) | GPR119JAK1GRM1GRM5PDK4 | |
| SCHEMBL2358167 | 0.83 | GPR119 (0.59) | GPR119JAK1GRM1GRM5PDK4 | |
| SCHEMBL30926321 | 0.83 | GPR119 (0.61) | GPR119JAK1GRM1GRM5PDK4 | |
| SCHEMBL27107338 | 0.82 | GPR119 (0.48) | GPR119JAK1GRM1GRM5PDK4 | |
| SCHEMBL23164876 | 0.82 | GPR119 (0.55) | GPR119JAK1GRM1GRM5PDK4 | |
| SCHEMBL31705698 | 0.80 | GRM1 (0.50) | GPR119JAK1GRM1GRM5PDK4 | |
| SCHEMBL31704677 | 0.80 | GRM1 (0.50) | GPR119JAK1GRM1GRM5PDK4 | |
| SCHEMBL31705574 | 0.79 | GPR119 (0.48) | GPR119GRM1GRM5PDK4NAMPT | |
| SCHEMBL31705452 | 0.79 | GPR119 (0.48) | GPR119GRM1GRM5PDK4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |