Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.55 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 9/20 | 0.45 |
| ▸ | GRM5 | P41594 | 8/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28816318 | 0.92 | GPR119 (0.47) | GPR119JAK1NAMPTGRM1GRM5 | |
| SCHEMBL2358167 | 0.82 | GPR119 (0.59) | GPR119JAK1NAMPTGRM1GRM5 | |
| SCHEMBL31705435 | 0.82 | GPR119 (0.56) | GPR119JAK1NAMPTGRM1GRM5 | |
| SCHEMBL31705807 | 0.82 | GPR119 (0.56) | GPR119JAK1NAMPTGRM1GRM5 | |
| SCHEMBL30926321 | 0.80 | GPR119 (0.61) | GPR119JAK1NAMPTGRM1GRM5 | |
| SCHEMBL23164675 | 0.80 | NAMPT (0.49) | GPR119JAK1NAMPTGRM1GRM5 | |
| SCHEMBL2357493 | 0.78 | GPR119 (0.57) | GPR119NAMPTGRM1GRM5PDK4 | |
| SCHEMBL20541569 | 0.77 | GPR119 (0.56) | GPR119JAK1GRM1GRM5PDK4 | |
| SCHEMBL5338430 | 0.77 | CDK5 (0.51) | GPR119NAMPTGRM1GRM5PDK4 | |
| SCHEMBL1199318 | 0.75 | GPR119 (0.53) | GPR119NAMPTGRM1GRM5PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041730-B1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2026-05-13 | — | — | EP | disclosed |
| US-12448395-B2 | Substituted bicyclic heteroaryl compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-10-21 | — | — | US | disclosed |
| CN-114761404-B | Substituted bicyclic heteroaryl compounds | 百时美施贵宝公司 | 2025-02-21 | — | — | CN | disclosed |
| US-20240124489-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2024-04-18 | — | — | US | disclosed |
| US-20230139171-A1 | SYSTEM AND METHOD FOR INSTRUCTING ONE OR MORE WEATHER DRONES | SITA INFORMATION NETWORKING COMPUTING UK LIMITED (GB) | 2023-05-04 | — | — | US | disclosed |
| US-20230139171-A1 | SYSTEM AND METHOD FOR INSTRUCTING ONE OR MORE WEATHER DRONES | SITA INFORMATION NETWORKING COMPUTING UK LIMITED (GB) | 2023-05-04 | — | — | US | disclosed |
| US-20230139171-A1 | SYSTEM AND METHOD FOR INSTRUCTING ONE OR MORE WEATHER DRONES | SITA INFORMATION NETWORKING COMPUTING UK LIMITED (GB) | 2023-05-04 | — | — | US | disclosed |
| EP-4041730-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | Bristol-Myers Squibb Company (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114761404-A | Substituted bicyclic heteroaryl compounds | 百时美施贵宝公司 | 2022-07-15 | — | — | CN | disclosed |
| WO-2021067326-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-04-08 | — | — | WO | disclosed |
| WO-2021067326-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124489-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | TLR7, TLR1, TLR9 | GPR119 79/4885JAK1 403/4885NAMPT 2420/4885 |
| US-12448395-B2 | Substituted bicyclic heteroaryl compounds | TLR7, TLR1, TLR9 | GPR119 79/4885JAK1 403/4885NAMPT 2420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.