Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31704694 | 0.85 | MAPT (0.37) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL31706914 | 0.79 | CNR2 (0.36) | ALDH1A1SMN1; SMN2MAPK1CNR2GPR183 | |
| SCHEMBL3946056 | 0.74 | CA1 (0.41) | MAPTALDH1A1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL31705458 | 0.73 | CKS1B (0.44) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL20163062 | 0.72 | CKS1B (0.52) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL31705426 | 0.69 | ALDH1A1 (0.42) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL31704865 | 0.68 | TDP1 (0.41) | MAPTALDH1A1TDP1RORCCYP2C9 | |
| Potassium Ion SCHEMBL31705065 | 0.68 | CKS1B (0.39) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL20898751 | 0.68 | KDM4E (0.40) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| Lithium Ion SCHEMBL31705008 | 0.67 | MAPT (0.34) | MAPTALDH1A1SMN1; SMN2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |