Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | SORD | Q00796 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706098 | 0.88 | CKS1B (0.55) | CKS1BSKP1SKP2LSSSORD | |
| Lithium Ion SCHEMBL31704621 | 0.88 | LSS (0.41) | CKS1BSKP1SKP2LSSSORD | |
| Lithium Ion SCHEMBL31705464 | 0.88 | LSS (0.41) | CKS1BSKP1SKP2LSSSORD | |
| SCHEMBL31706640 | 0.86 | TRPV1 (0.40) | CKS1BSKP1SKP2LSSSORD | |
| SCHEMBL31705685 | 0.86 | TRPV1 (0.40) | CKS1BSKP1SKP2LSSSORD | |
| SCHEMBL31705426 | 0.79 | ALDH1A1 (0.42) | CKS1BSKP1SKP2KDM4EALDH1A1 | |
| SCHEMBL21880062 | 0.76 | KMO (0.53) | SORDPIK3CAALDH1A1GBA1KMO | |
| Lithium Ion SCHEMBL31706628 | 0.76 | CKS1B (0.50) | CKS1BSKP1SKP2LSSSORD | |
| Lithium Ion SCHEMBL31705926 | 0.76 | CKS1B (0.50) | CKS1BSKP1SKP2LSSSORD | |
| SCHEMBL31704996 | 0.75 | CKS1B (0.55) | CKS1BSKP1SKP2SORDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |