Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31705446 | 0.89 | MYC (0.40) | MYCALDH1A1NPSR1HPGDGRM5 | |
| SCHEMBL31705400 | 0.86 | CNR2 (0.36) | MYCALDH1A1NPSR1HPGDGRM5 | |
| Lithium Ion SCHEMBL31705507 | 0.85 | NAMPT (0.30) | — | |
| SCHEMBL31705394 | 0.73 | CHRM4 (0.34) | ALDH1A1NPSR1HPGD | |
| Lithium Ion SCHEMBL31706629 | 0.70 | GRM5 (0.40) | MYCALDH1A1GRM5 | |
| Lithium Ion SCHEMBL31705741 | 0.70 | NAMPT (0.41) | ALDH1A1 | |
| Lithium Ion SCHEMBL31704850 | 0.68 | NAMPT (0.42) | ALDH1A1 | |
| Lithium Ion SCHEMBL31705374 | 0.68 | NAMPT (0.42) | ALDH1A1 | |
| Lithium Ion SCHEMBL31705499 | 0.65 | NAMPT (0.40) | ALDH1A1 | |
| SCHEMBL25246854 | 0.60 | TSHR (0.39) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |