Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 5/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706377 | 0.91 | PDGFRB (0.33) | EGFRIGF1RSRCFLT4KDR | |
| SCHEMBL31706869 | 0.85 | MCHR1 (0.34) | EGFRIGF1RSRCFLT4KDR | |
| SCHEMBL31706882 | 0.82 | KDR (0.31) | EGFRIGF1RSRCFLT4KDR | |
| SCHEMBL31706595 | 0.81 | EGFR (0.35) | EGFRIGF1RSRCFLT4KDR | |
| SCHEMBL31706879 | 0.81 | TBK1 (0.37) | — | |
| SCHEMBL31706175 | 0.80 | — | — | |
| SCHEMBL31707021 | 0.80 | EGFR (0.30) | EGFRIGF1RSRCFLT4KDR | |
| SCHEMBL31707014 | 0.80 | — | — | |
| SCHEMBL31705200 | 0.73 | RXFP1 (0.39) | RAB9AKMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL31705713 | 0.72 | EPHX2 (0.34) | ITKRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215558-A1 | COMPOUNDS FOR SPLICING MODULATION | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-10-16 | — | — | WO | disclosed |