Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31705877 | 0.85 | TUBB4A (0.39) | EGFRIGF1RSRCFLT4KDR | |
| SCHEMBL31707010 | 0.83 | NPC1 (0.38) | NPC1F11MAPT | |
| SCHEMBL31706178 | 0.81 | EGFR (0.37) | EGFRIGF1RSRCFLT4KDR | |
| SCHEMBL31706377 | 0.80 | PDGFRB (0.33) | EGFRIGF1RSRCFLT4KDR | |
| SCHEMBL31706870 | 0.80 | MAPT (0.38) | HPGDTUBB1HDAC1ALDH1A1MAPT | |
| SCHEMBL30552644 | 0.79 | NPC1 (0.41) | HPGDNPC1F11ALDH1A1MAPT | |
| SCHEMBL31706869 | 0.79 | MCHR1 (0.34) | EGFRIGF1RSRCFLT4KDR | |
| SCHEMBL31453156 | 0.75 | NPC1 (0.39) | HPGDTDP1NPC1ALDH1A1MAPT | |
| SCHEMBL31706882 | 0.75 | KDR (0.31) | EGFRIGF1RSRCFLT4KDR | |
| SCHEMBL22774174 | 0.72 | NPC1 (0.38) | NPC1F11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215558-A1 | COMPOUNDS FOR SPLICING MODULATION | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-10-16 | — | — | WO | claimed |
| WO-2025215558-A1 | COMPOUNDS FOR SPLICING MODULATION | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-10-16 | — | — | WO | disclosed |