Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 9/20 | 0.45 |
| ▸ | GRM5 | P41594 | 8/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | QDPR | P09417 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706901 | 1.00 | NAMPT (0.50) | NAMPTPDK4GRM1GRM5ESR2 | |
| SCHEMBL31704569 | 0.85 | CDK7 (0.49) | NAMPTPDK4GRM1GRM5JAK1 | |
| SCHEMBL2951348 | 0.85 | NAMPT (0.60) | NAMPTPDK4GRM1GRM5JAK1 | |
| SCHEMBL22324970 | 0.84 | NAMPT (0.55) | NAMPTPDK4GRM1GRM5JAK1 | |
| SCHEMBL31706789 | 0.84 | NAMPT (0.55) | NAMPTPDK4GRM1GRM5JAK1 | |
| SCHEMBL31705879 | 0.83 | CYP11B2 (0.56) | NAMPTPDK4GRM1GRM5JAK1 | |
| SCHEMBL24310781 | 0.83 | GRM1 (0.52) | NAMPTPDK4GRM1GRM5ESR2 | |
| SCHEMBL29567698 | 0.83 | GRM1 (0.52) | NAMPTPDK4GRM1GRM5ESR2 | |
| SCHEMBL31706443 | 0.82 | ESR2 (0.45) | NAMPTESR2CA12CA1CA2 | |
| SCHEMBL31704979 | 0.82 | ESR2 (0.45) | NAMPTESR2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |