Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 10/20 | 0.47 |
| ▸ | GRM5 | P41594 | 10/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.45 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31704818 | 0.85 | QDPR (0.51) | CYP11B2NAMPTATM | |
| SCHEMBL13473291 | 0.85 | CYP11B2 (0.61) | CYP11B2NAMPTGRM1GRM5JAK1 | |
| SCHEMBL29580862 | 0.84 | CYP11B2 (0.58) | CYP11B2NAMPTGRM1GRM5JAK1 | |
| SCHEMBL20753874 | 0.84 | CYP11B2 (0.58) | CYP11B2NAMPTGRM1GRM5JAK1 | |
| SCHEMBL2951348 | 0.84 | NAMPT (0.60) | CYP11B2NAMPTGRM1GRM5JAK1 | |
| SCHEMBL31706901 | 0.83 | NAMPT (0.50) | CYP11B2NAMPTGRM1GRM5JAK1 | |
| SCHEMBL31706237 | 0.83 | NAMPT (0.50) | CYP11B2NAMPTGRM1GRM5JAK1 | |
| SCHEMBL22324970 | 0.83 | NAMPT (0.55) | CYP11B2NAMPTGRM1GRM5JAK1 | |
| SCHEMBL31706789 | 0.83 | NAMPT (0.55) | CYP11B2NAMPTGRM1GRM5JAK1 | |
| SCHEMBL16271570 | 0.83 | CYP11B2 (0.61) | CYP11B2NAMPTGRM1GRM5JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |