SCHEMBL31706591

SCHEMBL31706591

COc1ccccc1-c1ccc2[nH]c(C(N)=O)cc2c1

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ABCB1 P08183 9/20 0.60
▸ ICMT O60725 1/20 0.52
▸ MAP2 P11137 1/20 0.47
▸ FLT3 P36888 4/20 0.47
▸ TNKS2 Q9H2K2 1/20 0.47
▸ PARP1 P09874 1/20 0.46
▸ PDGFRB P09619 1/20 0.46
▸ PDGFRA P16234 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31706772 0.88 ABCB1 (0.61) ABCB1FLT3TNKS2
SCHEMBL5745913 0.83 KDM4E (0.62) ABCB1
SCHEMBL31706449 0.78 MAP2 (0.48) MAP2FLT3PARP1
SCHEMBL31705716 0.76 LOXL2 (0.66) ABCB1ICMTTNKS2
SCHEMBL1081684 0.76 TNKS2 (0.61) ABCB1ICMTTNKS2PDGFRBPDGFRA
SCHEMBL29540321 0.75 PDGFRB (0.77) FLT3PDGFRBPDGFRA
SCHEMBL1429381 0.75 PDGFRB (0.77) FLT3PDGFRBPDGFRA
SCHEMBL28208771 0.74 KDM4E (0.55) ABCB1FLT3PDGFRB
SCHEMBL28046669 0.73 ROCK2 (0.48) MAP2PARP1
SCHEMBL5023244 0.73 PARP1 (0.50) ICMTTNKS2PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025215558-A1 COMPOUNDS FOR SPLICING MODULATION FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2025-10-16 — — WO disclosed
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