Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622531 | 0.98 | TSHR (0.47) | TSHRALOX15SCN5ASCN9ASCN10A | |
| SCHEMBL31706520 | 0.98 | TSHR (0.47) | TSHRALOX15SCN5ASCN9ASCN10A | |
| SCHEMBL1772459 | 0.79 | LMNA (0.60) | CYP1A2CYP3A4MEN1CYP2C9CYP2C19 | |
| SCHEMBL13408055 | 0.79 | TSHR (0.51) | TSHRALOX15SCN5ASCN9ASCN10A | |
| SCHEMBL5873464 | 0.77 | GABRA1 (0.50) | TSHRALOX15SCN5ASCN9ASCN10A | |
| SCHEMBL13408054 | 0.76 | TSHR (0.47) | TSHRALOX15SCN5ASCN9ASCN10A | |
| SCHEMBL11112611 | 0.76 | TSHR (0.47) | TSHRALOX15SCN5ASCN9ASCN10A | |
| SCHEMBL10299386 | 0.76 | TSHR (0.49) | TSHRALOX15SCN5ASCN9ASCN10A | |
| SCHEMBL31706097 | 0.75 | TSHR (0.46) | TSHRALOX15SCN5ASCN9ASCN10A | |
| SCHEMBL12414979 | 0.74 | TSHR (0.48) | TSHRALOX15SCN5ASCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217552-A1 | 2-(TERT-BUTYL)-4-METHYLPHENYL APPENDED 1,4-DIAZEPANE BASED NOVEL TFEB ACTIVATING COMPOUNDS AS AUTOPHAGY MODULATORS FOR NEURODEGENERATIVE DISORDERS INCLUDING ALZHEIMER'S DISEASE (AD) | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2025-10-16 | — | — | WO | disclosed |