SCHEMBL31707285

SCHEMBL31707285

NC(=O)c1csc2c1CNCC2

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PNMT P11086 3/20 0.46
MAPK8 P45983 1/20 0.42
CSNK1A1 P48729 1/20 0.42
LIMK1 P53667 1/20 0.42
MAP2K1 Q02750 1/20 0.42
PRKAA1 Q13131 1/20 0.42
DYRK1A Q13627 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
DYRK1B Q9Y463 1/20 0.42
PARP1 P09874 8/20 0.37
PARP2 Q9UGN5 8/20 0.37
HTR6 P50406 1/20 0.36
HPGD P15428 3/20 0.36
ALDH1A1 P00352 1/20 0.34
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL351180 0.87 PNMT (0.43) PNMTMAPK8CSNK1A1LIMK1MAP2K1
Hydrochloric Acid SCHEMBL16961478 0.85 PNMT (0.42) PNMTMAPK8CSNK1A1LIMK1MAP2K1
SCHEMBL17798356 0.80 MAPT (0.41) PNMTLIMK1DYRK1ACLK4DYRK1B
SCHEMBL6408001 0.75 HPGD (0.54) HPGDALDH1A1HTTL3MBTL1SMN1; SMN2
SCHEMBL3121683 0.75 HPGD (0.58) HPGDALDH1A1HTTL3MBTL1SMN1; SMN2
Hydrochloric Acid SCHEMBL31699313 0.75 ADORA1 (0.50) HPGDALDH1A1HTTL3MBTL1SMN1; SMN2
SCHEMBL2182641 0.74 HPGD (0.61) HPGDALDH1A1HTTL3MBTL1SMN1; SMN2
SCHEMBL28872765 0.73 MAPK8 (0.39) MAPK8CSNK1A1LIMK1MAP2K1PRKAA1
SCHEMBL21597376 0.73 HPGD (0.50) HPGDALDH1A1HTTL3MBTL1SMN1; SMN2
SCHEMBL3715448 0.71 PTPRC (0.42) PNMTMAPK8CSNK1A1LIMK1PRKAA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025215579-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS PFIZER INC. (US) 2025-10-16 WO disclosed