Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30276861 | 0.86 | ALOX5 (0.44) | SLC22A6NR4A2MTNR1AMTNR1BALOX5 | |
| SCHEMBL31708138 | 0.86 | SLC22A6 (0.44) | SLC22A6NR4A2MTNR1AMTNR1BALOX5 | |
| SCHEMBL30712078 | 0.85 | SLC22A6 (0.50) | SLC22A6NR4A2MTNR1AMTNR1BPBRM1 | |
| SCHEMBL31708098 | 0.84 | ALOX5 (0.43) | SLC22A6NR4A2MTNR1AMTNR1BALOX5 | |
| SCHEMBL31708071 | 0.84 | RAB9A (0.52) | SLC22A6NR4A2MTNR1AMTNR1BHSD17B10 | |
| SCHEMBL20898149 | 0.84 | SLC22A6 (0.49) | SLC22A6NR4A2MTNR1AMTNR1BPBRM1 | |
| SCHEMBL29504147 | 0.84 | SLC22A6 (0.49) | SLC22A6NR4A2MTNR1AMTNR1BPBRM1 | |
| SCHEMBL25792506 | 0.83 | SLC22A6 (0.58) | SLC22A6NR4A2MTNR1AMTNR1BPBRM1 | |
| SCHEMBL31708212 | 0.83 | MAPT (0.44) | SLC22A6MTNR1AMTNR1BALOX5RAB9A | |
| SCHEMBL31708107 | 0.82 | ALOX5 (0.41) | SLC22A6NR4A2MTNR1AMTNR1BALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635492-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | Gilgamesh Pharmaceuticals, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |