SCHEMBL3170865

SCHEMBL3170865

O=C1[C]=Cc2cc3ccccc3cc2C1=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.34
ALDH1A1 P00352 4/20 0.33
TP53 P04637 3/20 0.33
CASP1 P29466 3/20 0.33
CASP7 P55210 3/20 0.33
RAB9A P51151 3/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
MAPK1 P28482 2/20 0.33
NPC1 O15118 2/20 0.33
TSHR P16473 1/20 0.33
HIF1A Q16665 1/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
LMNA P02545 2/20 0.33
POLB P06746 2/20 0.33
HTT P42858 2/20 0.33
GAA P10253 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL725425 0.75 MEN1 (0.45) ALDH1A1TP53CASP7RAB9AHPGD
SCHEMBL29364188 0.69 MEN1 (0.56) GSTP1ALDH1A1TP53CASP1CASP7
SCHEMBL30130196 0.69 MEN1 (0.56) GSTP1ALDH1A1TP53CASP1CASP7
SCHEMBL354514 0.69 MEN1 (0.56) GSTP1ALDH1A1TP53CASP1CASP7
SCHEMBL1118356 0.68 PTPRC (0.57) GSTP1ALDH1A1TP53CASP1CASP7
SCHEMBL29349820 0.68 PTPRC (0.57) GSTP1ALDH1A1TP53CASP1CASP7
SCHEMBL29223851 0.68 GSTP1 (0.37) GSTP1ALDH1A1TP53CASP1CASP7
SCHEMBL2106709 0.68 GSTP1 (0.43) GSTP1ALDH1A1TP53CASP1CASP7
SCHEMBL2142756 0.67 DNMT1 (0.49) ALDH1A1TP53RAB9AHPGDHSD17B10
SCHEMBL7315832 0.67 ALDH1A1 (0.50) ALDH1A1CASP1CASP7HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1021415-A1 TRICYCLIC AMINOALKYLCARBOXAMIDES; NOVEL DOPAMINE D 3? RECEPTOR SUBTYPE SPECIFIC LIGANDS NEUROGEN CORPORATION (US) 2000-07-26 EP claimed
US-5910586-A Tricyclic aminoalkylcarboxamides; dopamine D3 receptor subtype specific ligands NEUROGEN CORPORATION (US) 1999-06-08 US claimed
US-5688950-A NERVOUS SYSTEM DISORDERS, SIDE EFFECT REDUCTION NEUROGEN CORPORATION (US) 1997-11-18 US claimed
WO-1997040015-A1 TRICYCLIC AMINOALKYLCARBOXAMIDES; NOVEL DOPAMINE D3 RECEPTOR SUBTYPE SPECIFIC LIGANDS NEUROGEN CORPORATION (US) 1997-10-30 WO claimed
US-4529804-A Naphthostyril Ni or Cu complexes, a process for their preparation, and high molecular weight organic material pigmented with these metal complexes CIBA-GEIGY CORPORATION (US) 1985-07-16 US claimed
EP-0008627-B1 QUINAZOLINE DERIVATIVES, AZO DYES DERIVED FROM THE QUINAZOLINES AND THEIR USE AS PIGMENTS BAYER AG (DE) 1984-10-03 EP claimed
US-4042577-A POLYESTERS, POLYAMIDES, CELLULOSE ACETATES SANDOZ LTD. (CH) 1977-08-16 US claimed
JP-63038944-A None JP disclosed
US-7828891-B2 organic pigment mixture excellent in dispersibility, dispersion stability and vividness; mixture of organic pigment and a compound R-N=N-CH(-CO-CH3)-CONH-C6H5 where R is naphthyl or anthraquinone, and the rings are substituted with at least one carboxy or sulfonic acid group DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2010-11-09 US disclosed
US-20100065794-A1 organic pigment mixture excellent in dispersibility, dispersion stability and vividness; mixture of organic pigment and a compound R-N=N-CH(-CO-CH3)-CONH-C6H5 where R is naphthyl or anthraquinone, and the rings are substituted with at least one carboxy or sulfonic acid group DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2010-03-18 US disclosed
US-7655087-B2 Dispersibility, dispersion stability, transparency, vividness; inkjet inks; used in printing inks, sizing colors, binder colors, coating materials, various coating formulations, dry toners and wet toners for electrophotography, thermal transfer recording inks DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2010-02-02 US disclosed
EP-1944339-A3 Pigment compositions, colored compositions making use of the pigment compositions, and color filters Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) 2009-07-01 EP disclosed
EP-1944339-A2 Pigment compositions, colored compositions making use of the pigment compositions, and color filters Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) 2008-07-16 EP disclosed
US-4822704-A IMPROVED SENSITIVITY AND DURABILITY FUJI XEROX CO., LTD. (JP) 1989-04-18 US disclosed
US-4820600-A Electrophotographic photoreceptor having a bisazo compound FUJI XEROX CO., LTD. (JP) 1989-04-11 US disclosed
JP-S6338944-A ELECTROPHOTOGRAPHIC SENSITIVE BODY FUJI XEROX CO LTD 1988-02-19 JP disclosed
US-4677155-A Anthroquinonyl photosensitive polymers CIBA-GEIGY CORPORATION (US) 1987-06-30 US disclosed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US disclosed
US-4198205-A SULFONIC ACID-FREE DISPERSE DYES BASF AKTIENGESELLSCHAFT (DE) 1980-04-15 US disclosed
US-4042577-A POLYESTERS, POLYAMIDES, CELLULOSE ACETATES SANDOZ LTD. (CH) 1977-08-16 US disclosed