SCHEMBL725425

SCHEMBL725425

O=C1[C]=Cc2ccccc2C1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
MAPT P10636 4/20 0.45
KDM4E B2RXH2 3/20 0.45
LMNA P02545 3/20 0.45
POLB P06746 3/20 0.45
CES1 P23141 3/20 0.45
IDO1 P14902 3/20 0.45
ALOX15 P16050 3/20 0.45
BCHE P06276 2/20 0.45
PTPRC P08575 2/20 0.45
THRB P10828 2/20 0.45
RECQL P46063 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.45
PKM P14618 1/20 0.45
PTPN1 P18031 1/20 0.45
ACHE P22303 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PTPN22 Q9Y2R2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL670373 0.86 EHMT2 (0.40) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL3170865 0.75 GSTP1 (0.34) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL7315832 0.72 ALDH1A1 (0.50) MEN1KMT2AMAPTKDM4EPOLB
SCHEMBL223194 0.67 IDO1 (0.48) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL28560306 0.65 MEN1 (0.41) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL3103996 0.64 MEN1 (0.33) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL292030 0.64 PTPN1 (0.70) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL3444897 0.64 CDC25B (0.57) MEN1KMT2AMAPTKDM4ELMNA
1,2-Naphthoquinone SCHEMBL173316 0.62 PTPRC (1.00) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL7721084 0.62 MEN1 (0.67) MEN1KMT2AMAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670864-B1 THERMALLY STABLE ANTHRAPYRIDONE COMPOSITIONS SABIC INNOVATIVE PLASTICS IP (NL) 2012-02-29 EP claimed
EP-1670864-A2 THERMALLY STABLE ANTHRAPYRIDONE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-06-21 EP claimed
US-6995266-B2 Thermally stable anthrapyridone compositions GENERAL ELECTRIC COMPANY (US) 2006-02-07 US claimed
WO-2005033210-A2 THERMALLY STABLE ANTHRAPYRIDONE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2005-04-14 WO claimed
US-20050075500-A1 Thermally stable anthrapyridone compositions SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2005-04-07 US claimed
EP-1670864-B1 THERMALLY STABLE ANTHRAPYRIDONE COMPOSITIONS SABIC INNOVATIVE PLASTICS IP (NL) 2012-02-29 EP disclosed
CN-101475549-A Sugar acid compound and use thereof UNIV EAST CHINA SCIENCE & TECH (CN) 2009-07-08 CN disclosed
EP-1670864-A2 THERMALLY STABLE ANTHRAPYRIDONE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-06-21 EP disclosed
US-20060106140-A1 Thermally stable anthrapyridone GENERAL ELECTRIC COMPANY (US) 2006-05-18 US disclosed
US-6995266-B2 Thermally stable anthrapyridone compositions GENERAL ELECTRIC COMPANY (US) 2006-02-07 US disclosed
WO-2005033210-A2 THERMALLY STABLE ANTHRAPYRIDONE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2005-04-14 WO disclosed
US-20050075500-A1 Thermally stable anthrapyridone compositions SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2005-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050075500-A1 Thermally stable anthrapyridone compositions IK, H1-0, H1-4 MEN1 2608/4885KMT2A 403/4885MAPT 3789/4885
US-20060106140-A1 Thermally stable anthrapyridone IK, H1-0, H1-4 MEN1 2830/4885KMT2A 482/4885MAPT 3791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.