Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31464103 | 0.92 | ALDH1A1 (0.48) | ALDH1A1ALOX15TDP1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL27142912 | 0.91 | ALDH1A1 (0.47) | ALDH1A1ALOX15TDP1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL27142909 | 0.91 | ALDH1A1 (0.47) | ALDH1A1ALOX15TDP1KDM4EPOLB | |
| SCHEMBL27149840 | 0.90 | ALDH1A1 (0.42) | ALDH1A1ALOX15TDP1KDM4EPOLB | |
| SCHEMBL27149842 | 0.90 | ALDH1A1 (0.42) | ALDH1A1ALOX15TDP1KDM4EPOLB | |
| SCHEMBL31464019 | 0.88 | ALDH1A1 (0.39) | ALDH1A1ALOX15TDP1KDM4EPOLB | |
| SCHEMBL31708691 | 0.87 | ALDH1A1 (0.41) | ALDH1A1ALOX15TDP1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL31464067 | 0.87 | ALDH1A1 (0.39) | ALDH1A1ALOX15TDP1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL27139895 | 0.87 | ALDH1A1 (0.39) | ALDH1A1ALOX15TDP1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL27139892 | 0.87 | ALDH1A1 (0.39) | ALDH1A1ALOX15TDP1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | ABCB11, ABCC1, SLC11A2 | ALDH1A1 774/4885ALOX15 1853/4885TDP1 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.