Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 5/20 | 0.33 |
| ▸ | GPR6 | P46095 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3160713 | 0.89 | GPR119 (0.44) | GPR119CYP2C9 | |
| SCHEMBL391003 | 0.89 | GPR119 (0.52) | GPR119CYP2C9 | |
| SCHEMBL3160341 | 0.79 | GPR119 (0.42) | GPR119CYP2C9ACACBGPR6 | |
| SCHEMBL386703 | 0.78 | GPR119 (0.56) | GPR119CYP2C9 | |
| SCHEMBL3169215 | 0.78 | GPR119 (0.54) | GPR119CYP2C9 | |
| SCHEMBL3162014 | 0.77 | GPR119 (0.40) | GPR119CYP2C9GPR6 | |
| SCHEMBL3166965 | 0.76 | GPR119 (0.47) | GPR119CYP2C9ACACB | |
| SCHEMBL3169834 | 0.76 | GPR119 (0.45) | GPR119CYP2C9 | |
| SCHEMBL3168299 | 0.76 | GPR119 (0.55) | GPR119CYP2C9ACACB | |
| SCHEMBL3160967 | 0.75 | GPR119 (0.54) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644357-B9 | TRISUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2010-03-24 | — | — | EP | claimed |
| EP-1644357-B1 | TRISUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2007-12-12 | — | — | EP | claimed |