Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 8/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31711218 | 0.86 | CHRNA4 (0.42) | KMT2AMAPTHTTTSHRSLC6A2 | |
| SCHEMBL27252088 | 0.83 | NPC1 (0.53) | KMT2AMEN1MAPTHTTSMN1; SMN2 | |
| SCHEMBL31710983 | 0.83 | SCD5 (0.39) | NPSR1KMT2AMEN1MAPTHTT | |
| SCHEMBL27252087 | 0.83 | NPSR1 (0.46) | NPSR1TP53KMT2AMEN1MAPT | |
| SCHEMBL31711143 | 0.83 | NPC1 (0.53) | KMT2AMEN1MAPTHTTSMN1; SMN2 | |
| SCHEMBL31711348 | 0.83 | NPSR1 (0.46) | NPSR1TP53KMT2AMEN1MAPT | |
| SCHEMBL31711024 | 0.83 | NPC1 (0.53) | KMT2AMEN1MAPTHTTSMN1; SMN2 | |
| SCHEMBL31711221 | 0.83 | SLC6A2 (0.38) | NPSR1KMT2AMEN1MAPTHTT | |
| SCHEMBL27252143 | 0.83 | NPSR1 (0.46) | NPSR1TP53KMT2AMEN1MAPT | |
| SCHEMBL27252150 | 0.83 | NPSR1 (0.46) | NPSR1TP53KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250325534-A1 | MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325534-A1 | MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES | IFNG, NOX1, CYP1A1 | NPSR1 2996/4885TP53 1835/4885KMT2A 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.