Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 2/20 | 0.49 |
| ▸ | JAK1 | P23458 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27293253 | 1.00 | TYK2 (0.49) | TYK2JAK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27294303 | 0.90 | ALDH1A1 (0.45) | TYK2JAK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27294126 | 0.85 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2ALDH1A1SYKTSHR | |
| SCHEMBL30923257 | 0.85 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2ALDH1A1SYKTSHR | |
| SCHEMBL27292564 | 0.84 | MAPT (0.48) | TYK2JAK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27294058 | 0.84 | TYK2 (0.55) | TYK2JAK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27417192 | 0.82 | JAK3 (0.49) | TYK2JAK1MAPTSMN1; SMN2SYK | |
| SCHEMBL30923185 | 0.82 | MAPT (0.46) | MAPTSMN1; SMN2ALDH1A1SYKTSHR | |
| SCHEMBL30923208 | 0.82 | MAPT (0.48) | MAPTSMN1; SMN2ALDH1A1SYKTSHR | |
| SCHEMBL27292717 | 0.82 | MAPT (0.46) | MAPTSMN1; SMN2ALDH1A1SYKTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4637738-A2 | INHIBITORS OF JAK2 | Llydaw Therapeutics, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |