SCHEMBL31712166

SCHEMBL31712166

O=C1C[C@H](ON2C(=O)c3ccccc3C2=O)CN1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
ALDH1A1 P00352 5/20 0.36
TSHR P16473 2/20 0.36
CYP1A2 P05177 2/20 0.36
CHRM2 P08172 1/20 0.36
OPRM1 P35372 1/20 0.36
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
IKZF3 Q9UKT9 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
MTNR1A P48039 1/20 0.36
HTR2C P28335 2/20 0.33
HTR2B P41595 2/20 0.33
VDR P11473 1/20 0.33
MEN1 O00255 1/20 0.33
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9388231 0.81 GAA (0.43) GAAALDH1A1TSHRCYP1A2CHRM2
SCHEMBL26931611 0.77 GAA (0.46) GAAALDH1A1TSHRCYP1A2CHRM2
SCHEMBL30728974 0.77 GAA (0.46) GAAALDH1A1TSHRCYP1A2CHRM2
SCHEMBL3078314 0.76 IDO1 (0.44) GAAALDH1A1CYP1A2KMT2AKDM4E
SCHEMBL24130978 0.74 ALDH1A1 (0.43) GAAALDH1A1TSHRCYP1A2CHRM2
SCHEMBL2077862 0.74 ALDH1A1 (0.47) GAAALDH1A1CYP1A2CHRM2OPRM1
SCHEMBL30002131 0.74 ALDH1A1 (0.47) GAAALDH1A1CYP1A2CHRM2OPRM1
SCHEMBL1526201 0.74 GAA (0.43) GAAALDH1A1CYP1A2KMT2AKDM4E
SCHEMBL32665351 0.73 HRH1 (0.46) GAAALDH1A1TSHRCYP1A2CHRM2
SCHEMBL2184889 0.73 HRH1 (0.46) GAAALDH1A1TSHRCYP1A2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4640688-A1 AVERMECTIN DERIVATIVE Meiji Seika Pharma Co., Ltd. (JP) 2025-10-29 EP disclosed