Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.43 |
| ▸ | CD38 | P28907 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29800333 | 0.88 | CSNK2A2 (0.51) | CSNK2A2CSNK2BARCSNK2A1NNMT | |
| SCHEMBL31712846 | 0.80 | LCK (0.40) | CSNK2A2CSNK2BEGFR | |
| SCHEMBL31712837 | 0.78 | MAPK10 (0.48) | CSNK2A2CSNK2BARCSNK2A1MAP4K4 | |
| SCHEMBL29649950 | 0.78 | EGFR (0.56) | CSNK2A2CSNK2BARNNMTSMN1; SMN2 | |
| SCHEMBL5676295 | 0.78 | EGFR (0.56) | CSNK2A2CSNK2BARNNMTSMN1; SMN2 | |
| SCHEMBL27881435 | 0.76 | EGFR (0.54) | CSNK2A2CSNK2BARNNMTSMN1; SMN2 | |
| SCHEMBL30504719 | 0.75 | CSNK2A2 (0.46) | CSNK2A2CSNK2BARCSNK2A1PKN1 | |
| SCHEMBL8003414 | 0.74 | PDE5A (0.45) | CD38PDE5AMAP4K4IP6K1NNMT | |
| SCHEMBL2051696 | 0.74 | EGFR (0.56) | CSNK2A2CSNK2BARCSNK2A1NNMT | |
| SCHEMBL15534806 | 0.72 | MAP2K7 (0.50) | CSNK2A2CSNK2BARCSNK2A1NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251624-B1 | TRICYCLIC CARBOXAMIDE DERIVATIVES AS PRMT5 INHIBITORS | AMGEN INC (US) | 2025-10-29 | — | — | EP | claimed |