Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31712837 | 0.72 | MAPK10 (0.48) | CHEK2FGFR1PKN1PKN2DYRK1A | |
| SCHEMBL30504719 | 0.72 | CSNK2A2 (0.46) | CHEK2PKN1PKN2ARKDM4E | |
| SCHEMBL29685371 | 0.71 | CHEK1 (0.43) | IP6K1APPHPGDSCHEK2FGFR1 | |
| SCHEMBL5635755 | 0.71 | RIPK1 (0.47) | IP6K1APPHPGDSCHEK2PKN1 | |
| SCHEMBL5636056 | 0.71 | AR (0.45) | IP6K1CHEK2ARKDM4EMAPT | |
| SCHEMBL26918721 | 0.71 | CHEK1 (0.43) | IP6K1APPHPGDSCHEK2FGFR1 | |
| Hydrochloric Acid SCHEMBL2366806 | 0.70 | AR (0.44) | IP6K1CHEK2ARKDM4EMAPT | |
| SCHEMBL27653205 | 0.70 | RIPK1 (0.46) | IP6K1APPHPGDSCHEK2PKN1 | |
| SCHEMBL30029315 | 0.70 | LCK (0.46) | IP6K1APPHPGDSNNMTSMN1; SMN2 | |
| SCHEMBL31605591 | 0.70 | LCK (0.46) | APPNNMTSMN1; SMN2LCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251624-B1 | TRICYCLIC CARBOXAMIDE DERIVATIVES AS PRMT5 INHIBITORS | AMGEN INC (US) | 2025-10-29 | — | — | EP | claimed |