Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | CTSS | P25774 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29988787 | 0.84 | CTSS (0.55) | CTSSKDM4ESMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL9220648 | 0.84 | CTSS (0.55) | CTSSKDM4ESMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL18422915 | 0.84 | CTSS (0.53) | KMT2ACTSSMEN1RAB9AKDM4E | |
| SCHEMBL18462193 | 0.84 | CTSS (0.57) | KMT2ACTSSMEN1RAB9AKDM4E | |
| SCHEMBL17116590 | 0.84 | CTSS (0.53) | KMT2ACTSSMEN1RAB9AKDM4E | |
| SCHEMBL30518569 | 0.84 | CTSS (0.53) | KMT2ACTSSMEN1RAB9AADORA2A | |
| SCHEMBL17117040 | 0.84 | CTSS (0.66) | KMT2ACTSSMEN1RAB9AKDM4E | |
| SCHEMBL17116374 | 0.83 | CTSS (0.49) | KMT2ACTSSMEN1RAB9AKDM4E | |
| SCHEMBL24345242 | 0.82 | CTSS (0.51) | KMT2ACTSSMEN1RAB9AKDM4E | |
| SCHEMBL27901818 | 0.82 | CTSS (0.51) | KMT2ACTSSMEN1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2873711-A1 | Platinum complexes | Centre National de la Recherche Scientifique (C.N.R.S.) (FR) | 2015-05-20 | — | — | EP | disclosed |
| EP-2081903-B1 | 2-AMINOCARBONYL-PYRIDINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2014-05-07 | — | — | EP | disclosed |
| US-8138348-B2 | Using coordination polymerization catalyst | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-8138348-B2 | Using coordination polymerization catalyst | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-8138348-B2 | Using coordination polymerization catalyst | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-8093250-B2 | 2-aminocarbonyl-pyridine derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2012-01-10 | — | — | US | disclosed |
| CN-101948366-A | Method for preparing 4- (diphenylamino) biaryl compound in water phase | UNIV DALIAN TECH | 2011-01-19 | — | — | CN | disclosed |
| US-20100286175-A1 | 2-(Pyridin-2-yl)-pyrimidines and Their Use for Controlling Harmful Fungi | GRAMMENOS WASSILIOS | 2010-11-11 | — | — | US | disclosed |
| US-7786043-B2 | 2-(pyridin-2-yl)-pyrimidines and their use for controlling harmful fungi | BASF AKTIENGESELLSCHAFT (DE) | 2010-08-31 | — | — | US | disclosed |
| US-7767665-B2 | 3-[6-(4-oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]propionic acid, having an excellent apoptosis inhibitory and Macrophage migration inhibitory factor (MIF) binding effects, used for preventing and/or treating cancers, AIDS, cardiovascular, neurodegeneartive, bone, kidney and liver disoders | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-03 | — | — | US | disclosed |
| US-7399759-B2 | 1, 3-benzothiazinone derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-07-15 | — | — | US | disclosed |
| WO-2008044217-A2 | 2-AMINOCARBONYL-PYRIDINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-04-17 | — | — | WO | disclosed |
| US-20080027085-A1 | 2-(Pyridin-2-Yl)-Pyrimidines and Their Use for Controlling Harmful Fungi | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-31 | — | — | US | disclosed |
| US-20050032786-A1 | 1, 3-benzothiazinone derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-02-10 | — | — | US | disclosed |
| EP-1424336-A1 | 1,3-BENZOTHIAZINONE DERIVATIVES AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-06-02 | — | — | EP | disclosed |
| EP-0259139-B1 | Pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL CO (JP) | 1994-01-26 | — | — | EP | disclosed |
| US-4868178-A | FUNGICIDE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1989-09-19 | — | — | US | disclosed |
| US-4783466-A | Novel pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-11-08 | — | — | US | disclosed |
| EP-0278610-A2 | Novel pyridinyl-s-triazine derivatives, method for production thereof and a fungicide containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-17 | — | — | EP | disclosed |
| EP-0259139-A2 | Pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027085-A1 | 2-(Pyridin-2-Yl)-Pyrimidines and Their Use for Controlling Harmful Fungi | CBR1, CBR3, CNPY2 | KMT2A 2701/4885CTSS 3882/4885MEN1 2335/4885 |
| US-20100286175-A1 | 2-(Pyridin-2-yl)-pyrimidines and Their Use for Controlling Harmful Fungi | CBR1, CBR3, CNPY2 | KMT2A 2701/4885CTSS 3987/4885MEN1 2404/4885 |
| US-20050032786-A1 | 1, 3-benzothiazinone derivatives and use thereof | MIF, MORF4L1, FOXM1 | KMT2A 3139/4885CTSS 3122/4885MEN1 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.