Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.53 |
| ▸ | GRK2 | P25098 | 3/20 | 0.50 |
| ▸ | GRK1 | Q15835 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31715259 | 0.83 | SCD (0.48) | PDE5AGRK2HDAC6SCDMMP13 | |
| SCHEMBL31715291 | 0.80 | HDAC6 (0.51) | PDE5AGRK2HDAC6SCD | |
| SCHEMBL2318142 | 0.75 | PDE5A (0.59) | PDE5AGRK2GRK1HDAC6SCD | |
| SCHEMBL31715261 | 0.75 | PDE5A (0.39) | PDE5AGRK2HDAC6SCDMMP13 | |
| SCHEMBL14478795 | 0.73 | PDE5A (0.65) | PDE5AGRK2GRK1HDAC6SCD | |
| SCHEMBL5532025 | 0.72 | RAB9A (0.65) | SCDCYP11B1CYP11B2MAPK1HTT | |
| SCHEMBL2317452 | 0.71 | MAPT (0.71) | PDE5AHDAC6MAPK1HTTSMN1; SMN2 | |
| SCHEMBL31715265 | 0.69 | PDE5A (0.38) | PDE5AHDAC6SCDMMP13TP53 | |
| SCHEMBL2315906 | 0.69 | HDAC6 (0.59) | PDE5AHDAC6SCDMMP13SMN1; SMN2 | |
| SCHEMBL2317671 | 0.68 | SCD (0.84) | PDE5AHDAC6SCDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025227148-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR TREATMENT OF HERPES VIRUSES | ASSEMBLY BIOSCIENCES, INC. (US) | 2025-10-30 | — | — | WO | disclosed |