Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23555570 | 0.87 | PDE5A (0.38) | PDE5AMMP13SCDHDAC6TRPA1 | |
| SCHEMBL31715277 | 0.85 | PDE5A (0.37) | PDE5AMMP13SCDHDAC6ENPP2 | |
| SCHEMBL31715278 | 0.84 | PDE5A (0.36) | PDE5AMMP13SCDHDAC6ENPP2 | |
| SCHEMBL23555296 | 0.80 | MAOA (0.33) | PDE5ASCDENPP2TRPA1TP53 | |
| SCHEMBL31715227 | 0.77 | CXCR3 (0.36) | MCHR1TP53ROCK2CCR2 | |
| SCHEMBL23555560 | 0.77 | TP53 (0.41) | PDE5ATRPA1TP53 | |
| SCHEMBL31715259 | 0.75 | SCD (0.48) | PDE5AMMP13SCDHDAC6TP53 | |
| SCHEMBL23555582 | 0.74 | LMNA (0.33) | TP53 | |
| SCHEMBL23555762 | 0.74 | SCD (0.43) | PDE5AMMP13SCDTRPA1TP53 | |
| SCHEMBL23555294 | 0.73 | PDE1A (0.41) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025227148-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR TREATMENT OF HERPES VIRUSES | ASSEMBLY BIOSCIENCES, INC. (US) | 2025-10-30 | — | — | WO | disclosed |