SCHEMBL31716428

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)O)[C@@H](C)O

nearest known ligand 0.68

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	17/20	0.68

▸	CALCR	P30988	17/20	0.68

▸	KEAP1	Q14145	1/20	0.51

▸	NMUR2	Q9GZQ4	1/20	0.48

▸	NMUR1	Q9HB89	1/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30974597	0.88	RAMP3 (0.68)	RAMP3CALCR
SCHEMBL30974349	0.88	RAMP3 (0.69)	RAMP3CALCR
SCHEMBL31031543	0.88	RAMP3 (0.66)	RAMP3CALCR
SCHEMBL30423163	0.87	RAMP3 (0.60)	RAMP3CALCR
SCHEMBL5578209	0.86	RAMP3 (0.59)	RAMP3CALCRKEAP1NMUR2NMUR1
SCHEMBL5578210	0.86	RAMP3 (0.59)	RAMP3CALCRKEAP1NMUR2NMUR1
SCHEMBL30536336	0.86	RAMP3 (0.61)	RAMP3CALCR
SCHEMBL30648440	0.85	RAMP3 (0.65)	RAMP3CALCR
SCHEMBL31232462	0.85	RAMP3 (0.54)	RAMP3CALCRNMUR2NMUR1
SCHEMBL30437447	0.85	RAMP3 (0.58)	RAMP3CALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025226506-A1	MONO- AND DUAL-AGONIST COMPOUNDS OF HUMAN GLP1R AND GIPR FOR OBESITY & T2DM	PROTAGONIST THERAPEUTICS, INC. (US)	2025-10-30	—	—	WO	disclosed