SCHEMBL317171

SCHEMBL317171

[CH2]C(O)CCOC(=O)C=C

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.56
ALDH1A1 P00352 4/20 0.56
TP53 P04637 3/20 0.56
HIF1A Q16665 3/20 0.56
CYP3A4 P08684 2/20 0.56
HSD17B10 Q99714 1/20 0.56
HPGD P15428 1/20 0.50
MAPK1 P28482 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
THRB P10828 2/20 0.42
ATM Q13315 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27970320 0.88 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10337184 0.84 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6368712 0.84 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL996461 0.84 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL709412 0.81 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27800526 0.81 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL142522 0.81 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9817924 0.81 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8660776 0.81 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27800524 0.81 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1136538-B1 USE OF A PHOTOCURABLE SEALING MATERIAL FOR OILY METAL SURFACES NICHIBAN KK (JP) 2006-10-18 EP claimed
US-11718758-B2 Aqueous dispersion of colored particles MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2023-08-08 US disclosed
CN-116263562-A Coloring composition, method for producing same, photosensitive coloring composition, color filter, solid-state imaging element, and image display device 东洋油墨SC控股株式会社 2023-06-16 CN disclosed
US-20220397712-A1 PHASE DIFFERENCE FILM, CIRCULARLY POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-12-15 US disclosed
WO-2022255210-A1 ADHESIVE AGENT COMPOSITION, ADHESIVE AGENT, AND SURFACE PROTECTION FILM 日東電工株式会社 2022-12-08 WO disclosed
US-20210071006-A1 AQUEOUS DISPERSION OF COLORED PARTICLES MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2021-03-11 US disclosed
EP-2983618-B1 PHAKIC LENS DEVICE WITH OPENINGS AND CONCENTRIC ANNULAR ZONES DAVE JAGRAT NATAVAR (IN) 2019-04-17 EP disclosed
US-20170304047-A1 INTRAOCULAR LENS CUSTOMIZED FOR ASTIGMATISM OR COMBINED ASTIGMATISM AND PRESBYOPIA DAVE, JAGRAT NATAVAR (IN) 2017-10-26 US disclosed
WO-2017167690-A1 NEGATIVE TYPE PHOTOSENSITIVE COMPOSITION CURABLE AT LOW TEMPERATURE AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2017-10-05 WO disclosed
WO-2017162831-A1 PHOTOSENSITIVE SILOXANE COMPOSITION AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2017-09-28 WO disclosed
WO-2012004746-A2 REFRACTIVE-DIFFRACTIVE OPHTHALMIC DEVICE AND COMPOSITIONS USEFUL FOR PRODUCING SAME POLYMER TECHNOLOGIES INTERNATIONAL (EOU) (IN) 2012-01-12 WO disclosed
US-20110261443-A1 HEAT RAY REFLECTIVE FILM AND LAMINATE THEREOF, AND COATING FLUID FOR FORMING HEAT RAY REFLECTIVE LAYER MITSUBISHI CHEMICAL CORPORATION (JP) 2011-10-27 US disclosed
EP-1887057-B1 ULTRAVIOLET-CURABLE INKJET INK, INKJET RECORDING METHOD AND INKJET RECORDER KONICA MINOLTA MED & GRAPHIC (JP) 2011-10-05 EP disclosed
EP-2361893-A1 HEAT RAY REFLECTIVE FILM AND LAMINATED PRODUCT THEREOF, AND COATING SOLUTION FOR FORMING HEAT RAY REFLECTIVE LAYER Mitsubishi Chemical Corporation (JP) 2011-08-31 EP disclosed
CN-101727002-A Radiation-sensitive resin composition, interlayer insulating film and microlens, and method for forming the same JSR CORP 2010-06-09 CN disclosed
CN-101384961-A Photosensitive resin composition, method for forming resist pattern, method for producing printed wiring board, and method for producing substrate for plasma display panel HITACHI CHEMICAL CO LTD (JP) 2009-03-11 CN disclosed
EP-1887057-A1 ULTRAVIOLET-CURABLE INKJET INK, INKJET RECORDING METHOD AND INKJET RECORDER Konica Minolta Medical & Graphic, Inc. (JP) 2008-02-13 EP disclosed
EP-1870440-A1 ACTINIC RADIATION CURABLE INK JET INK, AND METHOD FOR IMAGE FORMATION AND INK JET RECORDING APPARATUS USING SAID INK Konica Minolta Medical & Graphic, Inc. (JP) 2007-12-26 EP disclosed
CN-100345898-C Liquid crystal compound composition and retardation film using same NIPPON KAYAKU KK (JP) 2007-10-31 CN disclosed
CN-1732218-A Liquid crystal composition and retardation film produced using the same NIPPON KAYAKU KK (JP) 2006-02-08 CN disclosed