SCHEMBL709412

SCHEMBL709412

C=CC(=O)OCCC(O)Cl

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.54
ALDH1A1 P00352 4/20 0.54
TP53 P04637 3/20 0.54
HIF1A Q16665 3/20 0.54
CYP3A4 P08684 2/20 0.54
HSD17B10 Q99714 1/20 0.54
HPGD P15428 1/20 0.48
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
THRB P10828 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL27654273 0.88 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10714314 0.85 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29185584 0.83 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL996461 0.83 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6368712 0.83 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29185576 0.83 ATM (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3360841 0.82 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3269816 0.82 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28183263 0.81 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL317171 0.81 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0170095-B1 ONE-PACKAGE AQUEOUS LATICES CONTAINING ALKALINE-CURABLE CROSSLINKING POLYMERS National Starch and Chemical Corporation (US) 1990-05-23 EP claimed
CN-110041825-B Ionized paint composite coating and preparation method thereof 闽江学院 2021-07-27 CN disclosed
CN-105754444-A Preparation method of modified anticorrosive raw lacquer paint 中国林业科学研究院林产化学工业研究所 2016-07-13 CN disclosed
EP-1991912-B1 TONER, VESSEL WITH THE TONER, DEVELOPER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE AND IMAGE FORMING METHOD RICOH CO LTD (JP) 2016-05-11 EP disclosed
CN-101268168-B Functionalized photoreactive compounds ROLIC AG (CH) 2016-01-20 CN disclosed
US-8124308-B2 Toner, vessel with the toner, developer, image forming apparatus and process cartridge and image forming method RICOH COMPANY. LTD. (JP) 2012-02-28 US disclosed
US-8026031-B2 Toner, vessel with the toner, developer, image forming apparatus and process cartridge and image forming method RICOH COMPANY, LTD. (JP) 2011-09-27 US disclosed
US-20110086308-A1 TONER, VESSEL WITH THE TONER, DEVELOPER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE AND IMAGE FORMING METHOD WATANABE NAOHIRO 2011-04-14 US disclosed
US-20090155709-A1 TONER, VESSEL WITH THE TONER, DEVELOPER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2009-06-18 US disclosed
US-7525720-B2 Process for producing sheet for electrophoretic display, sheet for electrophoretic display, and its use NIPPON SHOKUBAI CO., LTD. (JP) 2009-04-28 US disclosed
WO-1997006127-A1 POLYMERS WITH CRYSTALLIZABLE FLUOROCARBON SIDE CHAINS, THEIR MONOMERS, AND SUBSTRATES COATED WITH THE POLYMERS W.L. GORE & ASSOCIATES, INC. (US) 1997-02-20 WO disclosed
US-5026742-A Containing dihydroxy (meth)acrylate and tertiary amine compound BASF AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed
EP-0234724-B1 OIL- AND WATER-REPELLENT COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-31 EP disclosed
US-4742140-A FLUROPOLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-03 US disclosed
EP-0234724-A1 Oil- and water-repellent copolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-09-02 EP disclosed
EP-0108985-B1 TRANSPARENT RESIN MATERIAL CONTAINING METAL ATOMS HITACHI, LTD. (JP) 1986-10-15 EP disclosed
US-4585841-A LENSES, WAVEGUIDES, OPTICAL FIBERS HITACHI, LTD. (JP) 1986-04-29 US disclosed
EP-0108985-A1 Transparent resin material containing metal atoms HITACHI, LTD. (JP) 1984-05-23 EP disclosed
US-4181761-A Shaped articles of ethylene-vinyl acetate copolymer having a coating of NCO-free radical-containing synthetic resin paint MITSUI POLYCHEMICALS CO., LTD. (JP) 1980-01-01 US disclosed
US-3945831-A Photosensitive resins containing a thienylacrylic acid ester or amide group FUJI PHOTO FILM CO., LTD. (JA) 1976-03-23 US disclosed