Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | MAP2K2 | P36507 | 5/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL695647 | 0.85 | CES2 (0.48) | CES2MAP2K2MAP2K1CFTRALDH1A1 | |
| SCHEMBL22180852 | 0.81 | CES2 (0.46) | CES2MAP2K1CFTRALDH1A1KDM4E | |
| SCHEMBL22163787 | 0.81 | CES2 (0.46) | CES2MAP2K1CFTRALDH1A1KDM4E | |
| SCHEMBL29789661 | 0.79 | CES2 (0.47) | CES2DGAT1GPR52ALDH1A1KDM4E | |
| SCHEMBL3782361 | 0.79 | GAA (0.53) | CES2DGAT1GPR52ALDH1A1KDM4E | |
| SCHEMBL24177167 | 0.79 | CES2 (0.47) | CES2DGAT1GPR52ALDH1A1KDM4E | |
| SCHEMBL29789763 | 0.79 | CES2 (0.47) | CES2DGAT1PARP1MAPK10KMT2A | |
| SCHEMBL1032909 | 0.79 | CES2 (0.47) | CES2DGAT1PARP1MAPK10KMT2A | |
| SCHEMBL1002163 | 0.79 | CES2 (0.72) | CES2CFTRGPR52ALDH1A1KDM4E | |
| SCHEMBL2425056 | 0.79 | CES2 (0.47) | CES2DGAT1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025224085-A1 | COMPOUNDS CAPABLE OF ACTING ON S1R AS WELL AS ON SEH AND USES THEREOF | UNIVERSITAT DE BARCELONA (ES) | 2025-10-30 | — | — | WO | disclosed |