Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | PTPRE | P23469 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31717592 | 0.85 | CES2 (0.46) | CES2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL22180852 | 0.85 | CES2 (0.46) | CES2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL22163787 | 0.85 | CES2 (0.46) | CES2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL2427821 | 0.80 | CFTR (0.55) | CES2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL7822002 | 0.80 | PTPRC (0.43) | ALDH1A1PTPRCPTPN2PTPN1PTPRA | |
| SCHEMBL940864 | 0.79 | RXRB (0.54) | CES2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL31000476 | 0.79 | RXRB (0.54) | CES2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL3036944 | 0.78 | ASPH (0.59) | CES2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL334641 | 0.78 | KEAP1 (0.52) | CES2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL187787 | 0.78 | ALDH1A1 (0.57) | CES2ALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025224085-A1 | COMPOUNDS CAPABLE OF ACTING ON S1R AS WELL AS ON SEH AND USES THEREOF | UNIVERSITAT DE BARCELONA (ES) | 2025-10-30 | — | — | WO | disclosed |
| CN-102741222-B | Haloalkyl-substituted amides as insecticides and acaricides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-02 | — | — | CN | disclosed |
| US-8889878-B2 | Haloalky-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2014-11-18 | — | — | US | disclosed |
| US-8889878-B2 | Haloalky-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2014-11-18 | — | — | US | disclosed |
| US-8889878-B2 | Haloalky-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2014-11-18 | — | — | US | disclosed |
| US-8710242-B2 | Haloalky -substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2014-04-29 | — | — | US | disclosed |
| US-20130172390-A1 | Haloalkyl-Substituted Amides as Insecticides and Acaricides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | US | disclosed |
| US-20130172390-A1 | Haloalkyl-Substituted Amides as Insecticides and Acaricides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | US | disclosed |
| US-20130172390-A1 | Haloalkyl-Substituted Amides as Insecticides and Acaricides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | US | disclosed |
| US-8399436-B2 | N-pyrazolyl carboxamides as CRAC channel inhibitors | GLAXO GROUP LIMITED (GB) | 2013-03-19 | — | — | US | disclosed |
| US-20090281138-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 066 | ASTRAZENECA AB (SE) | 2009-11-12 | — | — | US | disclosed |
| US-20090281138-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 066 | ASTRAZENECA AB (SE) | 2009-11-12 | — | — | US | disclosed |
| US-20090281138-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 066 | ASTRAZENECA AB (SE) | 2009-11-12 | — | — | US | disclosed |
| WO-2009064250-A1 | BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 065 | ASTRAZENECA AB (SE) | 2009-05-22 | — | — | WO | disclosed |
| WO-2009064250-A1 | BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 065 | ASTRAZENECA AB (SE) | 2009-05-22 | — | — | WO | disclosed |
| WO-2009064251-A1 | BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 066 | ASTRAZENECA AB (SE) | 2009-05-22 | — | — | WO | disclosed |
| WO-2009064251-A1 | BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 066 | ASTRAZENECA AB (SE) | 2009-05-22 | — | — | WO | disclosed |
| US-20090131468-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 065 | ASTRAZENECA AB (SE) | 2009-05-21 | — | — | US | disclosed |
| US-20090131468-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 065 | ASTRAZENECA AB (SE) | 2009-05-21 | — | — | US | disclosed |
| US-20090131468-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 065 | ASTRAZENECA AB (SE) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131468-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 065 | PTGER1, CYP3A5, SULT1E1 | CES2 293/4885ALDH1A1 122/4885HPGD 211/4885 |
| US-20090281138-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 066 | CYP2D6, PTGER1, CYP2B6 | CES2 307/4885ALDH1A1 85/4885HPGD 232/4885 |
| US-20130172390-A1 | Haloalkyl-Substituted Amides as Insecticides and Acaricides | CRYAA, ACLY, CRYZ | CES2 253/4885ALDH1A1 769/4885HPGD 3707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.