Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15751249 | 0.85 | SIGMAR1 (0.53) | SIGMAR1CCR5TMEM97CHRM5HTR1A | |
| SCHEMBL1058888 | 0.84 | SIGMAR1 (0.60) | SIGMAR1CCR5CHRM5HTR2CALDH1A1 | |
| SCHEMBL27866758 | 0.82 | SIGMAR1 (0.51) | SIGMAR1CCR5TMEM97CHRM5HTR1A | |
| SCHEMBL8029227 | 0.82 | SIGMAR1 (0.64) | SIGMAR1CCR5ALDH1A1ENPP2 | |
| SCHEMBL21997466 | 0.81 | SIGMAR1 (0.50) | SIGMAR1CCR5TMEM97CHRM5HTR1A | |
| SCHEMBL21998065 | 0.81 | SIGMAR1 (0.46) | SIGMAR1CCR5TMEM97CHRM5HTR1A | |
| SCHEMBL21998108 | 0.81 | SIGMAR1 (0.49) | SIGMAR1CCR5TMEM97CHRM5HTR1A | |
| SCHEMBL21997212 | 0.81 | SIGMAR1 (0.49) | SIGMAR1CCR5TMEM97CHRM5HTR1A | |
| SCHEMBL6356355 | 0.81 | SIGMAR1 (0.49) | SIGMAR1CCR5ALDH1A1ENPP2 | |
| SCHEMBL31734241 | 0.81 | SIGMAR1 (0.49) | SIGMAR1CCR5TMEM97CHRM5HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025224168-A1 | ARYL SULFONE AND SULFANONE DERIVATIVES AS OREXIN RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-10-30 | — | — | WO | disclosed |