SCHEMBL31718136

SCHEMBL31718136

NC(=O)c1nc(-c2ccc(O)cc2O)cs1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TYR P14679 12/20 0.64
AMY1A P0DUB6 5/20 0.55
CSNK2A1 P68400 1/20 0.53
MEN1 O00255 2/20 0.52
POLB P06746 2/20 0.52
GAA P10253 2/20 0.52
MAPT P10636 2/20 0.52
KMT2A Q03164 2/20 0.52
KDM4E B2RXH2 1/20 0.52
HPGD P15428 1/20 0.52
VCP P55072 1/20 0.52
GFER P55789 1/20 0.52
PIM1 P11309 1/20 0.50
ALDH1A1 P00352 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6685526 1.00 TYR (0.64) TYRAMY1ACSNK2A1MEN1POLB
SCHEMBL6686667 0.83 HTR2B (0.56) TYRAMY1AMEN1MAPTKMT2A
SCHEMBL29213708 0.80 TYR (0.62) TYRAMY1ACSNK2A1MEN1POLB
SCHEMBL6687941 0.79 LTA4H (0.61) AMY1AMEN1POLBGAAMAPT
SCHEMBL6685534 0.78 TYR (1.00) TYRAMY1AMEN1POLBGAA
SCHEMBL31137885 0.78 TYR (0.59) TYRAMY1ACSNK2A1MEN1POLB
SCHEMBL5999257 0.76 KDM4E (0.55) AMY1ACSNK2A1MEN1POLBMAPT
SCHEMBL16238657 0.76 MAPT (0.51) MEN1POLBMAPTKMT2AKDM4E
SCHEMBL21835963 0.76 TYR (0.56) TYRAMY1ACSNK2A1MEN1POLB
SCHEMBL29213706 0.76 TYR (0.71) TYRAMY1ACSNK2A1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120887849-A 4- (2, 4-Dihydroxyphenyl) thiazole-2-carboxamide derivative and preparation method and application thereof 广东药科大学 2025-11-04 CN disclosed