Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 10/20 | 1.00 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.59 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.59 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | VCP | P55072 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10315919 | 0.84 | TYR (0.73) | TYRLTA4HMKNK1MKNK2MAPT | |
| SCHEMBL6686670 | 0.79 | TYR (0.66) | TYRLTA4HMKNK1MKNK2AMY1A | |
| SCHEMBL6637678 | 0.78 | LTA4H (0.65) | TYRLTA4HMKNK1MKNK2AMY1A | |
| SCHEMBL6685526 | 0.78 | TYR (0.64) | TYRAMY1AMAPTRAB9AMEN1 | |
| SCHEMBL31718136 | 0.78 | TYR (0.64) | TYRAMY1AMAPTRAB9AMEN1 | |
| SCHEMBL29213708 | 0.77 | TYR (0.62) | TYRAMY1AMAPTNPC1RAB9A | |
| SCHEMBL12297549 | 0.76 | TYR (0.71) | TYRAMY1AMAPTNPC1RAB9A | |
| SCHEMBL10315909 | 0.75 | TYR (0.60) | TYRLTA4HMKNK1MKNK2MAPT | |
| SCHEMBL12647588 | 0.75 | TYR (0.60) | TYRLTA4HMKNK1MKNK2MAPT | |
| SCHEMBL31137885 | 0.75 | TYR (0.59) | TYRAMY1AMAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040224992-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-11-11 | — | — | US | claimed |
| WO-2004075864-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-09-10 | — | — | WO | claimed |
| EP-4729513-A1 | A-KETO ACID AMIDE OR SUBSTITUTED OXALIC ACID AMIDE ESTER COMPOUND AND COMPOSITION THEREOF | Nanjing Chempion Biotechnology Co., Ltd. (CN) | 2026-04-22 | — | — | EP | disclosed |
| WO-2025001687-A1 | Α-KETO ACID AMIDE OR SUBSTITUTED OXALIC ACID AMIDE ESTER COMPOUND AND COMPOSITION THEREOF | 南京桦冠生物技术有限公司 | 2025-01-02 | — | — | WO | disclosed |
| EP-4165029-B1 | PROCESS FOR THE MANUFACTURE OF ALKYLAMIDOTHIAZOLES | DSM IP ASSETS BV (NL) | 2024-07-17 | — | — | EP | disclosed |
| CN-117820251-B | Bis-alpha-keto acid amide compound and composition thereof | 南京桦冠生物技术有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117820251-A | Bis-alpha-keto acid amide compound and composition thereof | 南京桦冠生物技术有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-116554122-B | Alpha-keto acid amide or substituted oxalic acid amide ester compound and composition thereof | 南京桦冠生物技术有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116554122-A | Alpha-keto acid amide or substituted oxalic acid amide ester compound and composition thereof | 南京桦冠生物技术有限公司 | 2023-08-08 | — | — | CN | disclosed |
| WO-2021255011-A1 | PROCESS FOR THE MANUFACTURE OF ALKYLAMIDOTHIAZOLES | DSM IP ASSETS B.V. (NL) | 2021-12-23 | — | — | WO | disclosed |
| WO-2020011470-A1 | SELF-ADHESIVE FLAT PRODUCTS CONTAINING ONE OR MORE ALKYLAMIDOTHIAZOLES | BEIERSDORF AG (DE) | 2020-01-16 | — | — | WO | disclosed |
| US-8920785-B2 | Cosmetic or dermatological preparations with a content of one or more thiazole derivates | BEIERSDORF AG (DE) | 2014-12-30 | — | — | US | disclosed |
| US-8920785-B2 | Cosmetic or dermatological preparations with a content of one or more thiazole derivates | BEIERSDORF AG (DE) | 2014-12-30 | — | — | US | disclosed |
| CN-103179947-A | Cosmetic or dermatological preparations comprising one or more thiazole derivatives | BEIERSDORF AG | 2013-06-26 | — | — | CN | disclosed |
| US-20040224992-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224992-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | NR3C1, NR3C2, MC2R | TYR 2446/4885LTA4H 170/4885MKNK1 2021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.