Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | LTK | P29376 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | PRKX | P51817 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | MST1R | Q04912 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3519434 | 0.83 | NOS1 (0.59) | NOS1TRPA1PLK4CHEK1AURKA | |
| SCHEMBL3064844 | 0.82 | NOS1 (0.63) | NOS1TRPA1PLK4CHEK1AURKA | |
| SCHEMBL4752843 | 0.74 | NOS1 (0.53) | NOS1PLK4CHEK1AURKADAPK3 | |
| SCHEMBL31539809 | 0.70 | NOS1 (0.48) | NOS1TRPA1PLK4CHEK1AURKA | |
| SCHEMBL5020194 | 0.70 | NOS1 (0.49) | NOS1TRPA1PLK4CHEK1AURKA | |
| SCHEMBL30741485 | 0.69 | NOS1 (0.47) | NOS1PLK4CHEK1AURKADAPK3 | |
| SCHEMBL14231151 | 0.69 | NOS1 (0.61) | NOS1PLK4CHEK1AURKADAPK3 | |
| SCHEMBL19920463 | 0.68 | RPS6KA2 (0.47) | NOS1TRPA1RETFGFR1KDM4E | |
| SCHEMBL23198253 | 0.68 | NOS1 (0.46) | NOS1PLK4CHEK1AURKADAPK3 | |
| SCHEMBL20997887 | 0.68 | NOS1 (0.46) | NOS1TRPA1PLK4CHEK1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025229494-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-11-06 | — | — | WO | disclosed |