SCHEMBL31722366

SCHEMBL31722366

CCCCOC(=O)COC1CNC1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.42
ALDH1A1 P00352 2/20 0.41
ATM Q13315 1/20 0.39
DGKA P23743 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
TSHR P16473 2/20 0.38
CHRM1 P11229 1/20 0.37
HPGD P15428 1/20 0.37
RAD52 P43351 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
EPHX2 P34913 1/20 0.36
GBA1 P04062 1/20 0.36
FAAH O00519 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30404743 0.85 DGKA (0.44) NAAAALDH1A1ATMDGKAEPHX2
SCHEMBL8948677 0.82 GAA (0.41) ALDH1A1TSHREPHX2
SCHEMBL5604986 0.80 NAAA (0.49) NAAAALDH1A1ATMDGKATDP1
SCHEMBL21384249 0.80 NAAA (0.42) NAAAALDH1A1ATMDGKATDP1
SCHEMBL21384301 0.79 NAAA (0.41) NAAAALDH1A1ATMDGKATDP1
SCHEMBL25545688 0.79 NAAA (0.41) NAAAALDH1A1ATMTDP1L3MBTL1
SCHEMBL21384182 0.78 NAAA (0.40) NAAAALDH1A1ATMDGKATDP1
SCHEMBL8714112 0.78 SMYD3 (0.40) NAAAALDH1A1ATMDGKATDP1
SCHEMBL8714110 0.78 SMYD3 (0.40) NAAAALDH1A1ATMDGKATDP1
SCHEMBL21384262 0.76 ATM (0.40) NAAAALDH1A1ATMDGKATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025228947-A1 BIFUNCTIONAL COMPOUNDS CAPABLE OF INDUCING DEGRADATION OF POLO-LIKE KINASE1 CROSSFIRE ONCOLOGY B.V. (NL) 2025-11-06 WO disclosed