SCHEMBL31722508

SCHEMBL31722508

Cc1ccc(C(=O)N2CCC(CN3CCC(CC(=O)O)CC3)CC2)cc1N1CCC(=O)NC1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 1/20 0.40
▸ CRBN Q96SW2 1/20 0.40
▸ TNKS O95271 1/20 0.40
▸ FFAR4 Q5NUL3 3/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ TP53 P04637 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ HTT P42858 1/20 0.38
▸ GFER P55789 1/20 0.38
▸ DRD2 P14416 1/20 0.37
▸ HTR2A P28223 1/20 0.37
▸ HTR2C P28335 1/20 0.37
▸ HTR2B P41595 1/20 0.37
▸ SIGMAR1 Q99720 1/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ NPBWR1 P48145 1/20 0.36
▸ MCHR1 Q99705 1/20 0.36
▸ LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30995326 0.84 DDB1 (0.42) DDB1CRBNTNKSALDH1A1TP53
SCHEMBL30966192 0.84 TNKS (0.46) DDB1CRBNTNKSFFAR4ALDH1A1
SCHEMBL30822383 0.82 FFAR4 (0.44) TNKSFFAR4ALDH1A1HPGDLMNA
SCHEMBL29227486 0.82 FFAR4 (0.44) TNKSFFAR4ALDH1A1HPGDLMNA
SCHEMBL30816878 0.81 GABRD (0.42) DDB1CRBNTNKSFFAR4GFER
SCHEMBL30816881 0.81 GABRD (0.42) DDB1CRBNTNKSFFAR4GFER
SCHEMBL30995353 0.81 DDB1 (0.46) DDB1CRBNTNKSALDH1A1TP53
SCHEMBL31722526 0.80 DDB1 (0.39) DDB1CRBNTNKSALDH1A1TP53
SCHEMBL30262817 0.79 DDB1 (0.44) DDB1CRBNTNKSALDH1A1SMN1; SMN2
SCHEMBL23134613 0.79 TSHR (0.40) TP53SMN1; SMN2KMT2ANPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025228947-A1 BIFUNCTIONAL COMPOUNDS CAPABLE OF INDUCING DEGRADATION OF POLO-LIKE KINASE1 CROSSFIRE ONCOLOGY B.V. (NL) 2025-11-06 — — WO disclosed
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