Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28978031 | 0.91 | CRBN (0.42) | DDB1CRBNHPGDALDH1A1TP53 | |
| SCHEMBL30266960 | 0.91 | CRBN (0.42) | DDB1CRBNHPGDALDH1A1TP53 | |
| SCHEMBL24670711 | 0.87 | HSD11B1 (0.43) | DDB1CRBNALDH1A1KMT2AHSD11B1 | |
| SCHEMBL29201743 | 0.87 | MGLL (0.42) | DDB1CRBNHPGDKMT2AHSD11B1 | |
| SCHEMBL31722472 | 0.87 | NR3C1 (0.43) | HPGDALDH1A1KMT2AHSD11B1MEN1 | |
| SCHEMBL25581205 | 0.87 | NR3C1 (0.43) | HPGDALDH1A1KMT2AHSD11B1MEN1 | |
| SCHEMBL30864113 | 0.86 | CRBN (0.40) | DDB1CRBNHPGDALDH1A1TP53 | |
| SCHEMBL30995326 | 0.85 | DDB1 (0.42) | DDB1CRBNHPGDALDH1A1TP53 | |
| SCHEMBL30816917 | 0.85 | CRBN (0.35) | DDB1CRBNHPGDALDH1A1TP53 | |
| SCHEMBL28783557 | 0.82 | DDB1 (0.44) | DDB1CRBNHPGDALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025228947-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF INDUCING DEGRADATION OF POLO-LIKE KINASE1 | CROSSFIRE ONCOLOGY B.V. (NL) | 2025-11-06 | — | — | WO | disclosed |
| EP-4634169-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | Pfizer Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024127297-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | PFIZER INC. (US) | 2024-06-20 | — | — | WO | disclosed |