Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29539987 | 0.86 | KCNH2 (0.60) | MAPTHPGDMCL1KDM4ERAB9A | |
| SCHEMBL13699685 | 0.85 | KDM4E (0.54) | POLBMAPTHPGDMCL1KDM4E | |
| SCHEMBL4655120 | 0.84 | MCL1 (0.71) | POLBMAPTHPGDMCL1KDM4E | |
| SCHEMBL17182567 | 0.83 | PRNP (0.51) | MAPTMCL1KDM4ERAB9AALDH1A1 | |
| SCHEMBL28120404 | 0.83 | MCL1 (0.49) | POLBMAPTHPGDMCL1KDM4E | |
| SCHEMBL23665644 | 0.80 | POLB (0.50) | POLBMAPTHPGDMCL1KDM4E | |
| SCHEMBL353910 | 0.79 | KCNH2 (0.58) | HPGDKDM4ERAB9AKMT2AMEN1 | |
| SCHEMBL17182580 | 0.79 | KDM4E (0.49) | MAPTHPGDMCL1KDM4EKMT2A | |
| SCHEMBL3501204 | 0.79 | MCL1 (0.58) | MAPTHPGDMCL1KDM4EALDH1A1 | |
| SCHEMBL20893358 | 0.78 | L3MBTL1 (0.61) | POLBMAPTHPGDKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229045-B1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | BROAD INST INC (US) | 2025-11-12 | — | — | EP | claimed |