Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498475 | 0.87 | MCL1 (0.78) | MCL1KDM4EALDH1A1HPGDKCNH2 | |
| SCHEMBL3500950 | 0.87 | MCL1 (0.60) | MCL1KDM4EALDH1A1HPGDKCNH2 | |
| SCHEMBL3501203 | 0.86 | MCL1 (0.58) | MCL1KDM4EALDH1A1HPGDKCNH2 | |
| SCHEMBL3499722 | 0.81 | HIF1A (0.55) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3498198 | 0.80 | KDM4E (0.43) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31723091 | 0.79 | POLB (0.52) | MCL1KDM4EALDH1A1HPGDKCNH2 | |
| SCHEMBL3500040 | 0.78 | MCL1 (0.53) | MCL1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL3498599 | 0.77 | KDM4E (0.61) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3498799 | 0.76 | MCL1 (0.51) | MCL1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL17182567 | 0.76 | PRNP (0.51) | MCL1KDM4EALDH1A1KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | MCL1 3727/4885KDM4E 2059/4885ALDH1A1 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.