Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | HPGD | P15428 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | ANO1 | Q5XXA6 | 6/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20918191 | 1.00 | MAPT (0.77) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31723167 | 0.91 | MAPT (0.62) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28427603 | 0.91 | MAPT (0.62) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL20918213 | 0.90 | MAPT (0.85) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31723182 | 0.90 | MAPT (0.85) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL20918210 | 0.89 | MAPT (0.74) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31723169 | 0.89 | MAPT (0.74) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL20918175 | 0.87 | ALDH1A1 (0.57) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31723124 | 0.87 | ALDH1A1 (0.57) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31723161 | 0.86 | GABRP (0.56) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3699174-B1 | COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME | ILAB (KR) | 2025-11-12 | — | — | EP | claimed |