SCHEMBL31723192

SCHEMBL31723192

Cc1ccccc1Nc1cc(Cl)cc(N)c1C

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 4/20 0.43
MAPK13 O15264 3/20 0.43
MAPK12 P53778 3/20 0.43
MAPK11 Q15759 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
CYP3A4 P08684 1/20 0.40
HTT P42858 1/20 0.40
P2RY2 P41231 1/20 0.39
P2RY4 P51582 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
LRRK2 Q5S007 1/20 0.39
TP53 P04637 1/20 0.39
SLC2A1 P11166 1/20 0.39
LMNA P02545 2/20 0.38
MAPK10 P53779 1/20 0.38
ALDH1A1 P00352 2/20 0.38
MCHR1 Q99705 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22232157 1.00 MAPK14 (0.43) MAPK14MAPK13MAPK12MAPK11SMN1; SMN2
SCHEMBL29454238 0.84 POLB (0.39) SMN1; SMN2NPC1RAB9ALMNAMAPK10
SCHEMBL31723263 0.84 POLB (0.39) SMN1; SMN2NPC1RAB9ALMNAMAPK10
SCHEMBL22232361 0.84 POLB (0.39) SMN1; SMN2NPC1RAB9ALMNAMAPK10
SCHEMBL22232365 0.81 GAA (0.50) MAPK14SMN1; SMN2CYP3A4HTTTP53
SCHEMBL22232279 0.80 MAPK13 (0.43) MAPK14MAPK13MAPK12MAPK11SMN1; SMN2
SCHEMBL22232656 0.77 CXCR2 (0.42)
SCHEMBL29454258 0.77 CXCR2 (0.42)
SCHEMBL31723253 0.75 FADS1 (0.47) SMN1; SMN2P2RY2P2RY4LMNA
SCHEMBL22231930 0.75 FADS1 (0.47) SMN1; SMN2P2RY2P2RY4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed