SCHEMBL31723263

SCHEMBL31723263

Cc1c(N)cc(Cl)cc1Nc1ccccc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.39
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
FABP3 P05413 1/20 0.38
FABP4 P15090 1/20 0.38
GRIK1 P39086 1/20 0.37
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPK10 P53779 1/20 0.36
ALDH1A1 P00352 3/20 0.36
CXCR2 P25025 1/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
USP2 O75604 1/20 0.36
HPGD P15428 1/20 0.36
NFKB1 P19838 1/20 0.36
RAB9A P51151 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22232361 1.00 POLB (0.39) POLBLMNAGAAKMT2AFABP3
SCHEMBL29454238 1.00 POLB (0.39) POLBLMNAGAAKMT2AFABP3
SCHEMBL29454339 0.84 CCNC (0.40) GAAMAPTSMN1; SMN2MAPK10ALDH1A1
SCHEMBL22232266 0.84 CCNC (0.40) GAAMAPTSMN1; SMN2MAPK10ALDH1A1
SCHEMBL31723192 0.84 MAPK14 (0.43) LMNASMN1; SMN2MAPK10ALDH1A1NPC1
SCHEMBL29454081 0.84 SLC6A4 (0.39) GAAKMT2AMAPTSMN1; SMN2MAPK10
SCHEMBL22232157 0.84 MAPK14 (0.43) LMNASMN1; SMN2MAPK10ALDH1A1NPC1
SCHEMBL29454099 0.84 CCNC (0.40) GAAMAPTSMN1; SMN2MAPK10ALDH1A1
SCHEMBL22232365 0.79 GAA (0.50) LMNAGAAKMT2AMAPTSMN1; SMN2
SCHEMBL22232656 0.77 CXCR2 (0.42) GAAMAPTCXCR2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP disclosed