SCHEMBL31723202

SCHEMBL31723202

COc1cccc(Nc2cc(F)cc(N)c2C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 2/20 0.51
GAA P10253 2/20 0.51
NPC1 O15118 1/20 0.51
RAPGEF4 Q8WZA2 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47
POLB P06746 1/20 0.47
TSHR P16473 2/20 0.46
HTT P42858 1/20 0.46
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
ROCK1 Q13464 1/20 0.45
EGFR P00533 1/20 0.43
PIK3CA P42336 1/20 0.43
PIK3CG P48736 1/20 0.43
SYK P43405 1/20 0.43
IDO1 P14902 1/20 0.43
MAPK14 Q16539 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454254 1.00 GFER (0.51) GFERGAANPC1RAPGEF4MEN1
SCHEMBL22232189 1.00 GFER (0.51) GFERGAANPC1RAPGEF4MEN1
SCHEMBL31723208 0.87 RAPGEF4 (0.49) GFERGAANPC1RAPGEF4MEN1
SCHEMBL11902277 0.84 GFER (0.54) GFERGAANPC1RAPGEF4MEN1
SCHEMBL29454098 0.84 RAPGEF4 (0.49) GAANPC1RAPGEF4MEN1KMT2A
SCHEMBL22232047 0.84 RAPGEF4 (0.49) GAANPC1RAPGEF4MEN1KMT2A
SCHEMBL31723264 0.84 RAPGEF4 (0.49) GAANPC1RAPGEF4MEN1KMT2A
SCHEMBL22231966 0.82 NPSR1 (0.47) NPC1RAPGEF4MAPTPOLBHTT
SCHEMBL31723222 0.82 NPSR1 (0.47) NPC1RAPGEF4MAPTPOLBHTT
SCHEMBL29454120 0.82 NPSR1 (0.47) NPC1RAPGEF4MAPTPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed