SCHEMBL31723219

SCHEMBL31723219

Cc1c(N)cc(F)cc1Nc1ncccn1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 6/20 0.37
F2 P00734 1/20 0.33
PLG P00747 1/20 0.33
PLAT P00750 1/20 0.33
KLK1 P06870 1/20 0.33
PRSS1 P07477 1/20 0.33
MAPK8 P45983 1/20 0.32
LIMK1 P53667 1/20 0.32
MST1R Q04912 1/20 0.32
MAPK14 Q16539 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
ALK Q9UM73 1/20 0.32
DYRK1B Q9Y463 1/20 0.32
NPC1 O15118 2/20 0.32
POLB P06746 2/20 0.32
RAB9A P51151 2/20 0.32
KMT2A Q03164 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HTT P42858 2/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22232534 1.00 PLAU (0.37) PLAUF2PLGPLATKLK1
SCHEMBL22231932 0.81 MEN1 (0.50) NPC1RAB9AKMT2ASMN1; SMN2MEN1
SCHEMBL29454061 0.81 MEN1 (0.50) NPC1RAB9AKMT2ASMN1; SMN2MEN1
SCHEMBL22231897 0.80 NR4A2 (0.40) PLAUF2PLGPLATKLK1
SCHEMBL31723187 0.80 NR4A2 (0.40) PLAUF2PLGPLATKLK1
SCHEMBL22232298 0.76 DHODH (0.46) POLBGRM4
SCHEMBL29454148 0.76 DHODH (0.46) POLBGRM4
SCHEMBL11901257 0.76 PLAU (0.41) PLAUF2PLGPLATKLK1
SCHEMBL29454211 0.75 RAPGEF4 (0.44) ALDH1A1MAPTTHRBTDP1GRM4
SCHEMBL31723226 0.75 KDM4E (0.37) DYRK1BNPC1RAB9AKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed