SCHEMBL31723226

SCHEMBL31723226

Cc1c(N)cc(F)cc1Nc1cnccn1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.37
ALDH1A1 P00352 3/20 0.37
HPGD P15428 2/20 0.37
MKNK1 Q9BUB5 1/20 0.37
CDK8 P49336 1/20 0.36
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
CDK9 P50750 1/20 0.36
CDK5 Q00535 1/20 0.36
DYRK1B Q9Y463 1/20 0.36
KMT2A Q03164 1/20 0.35
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
JAK2 O60674 1/20 0.33
JAK1 P23458 1/20 0.33
TYK2 P29597 1/20 0.33
JAK3 P52333 1/20 0.33
LCK P06239 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22232338 1.00 KDM4E (0.37) KDM4EALDH1A1HPGDMKNK1CDK8
SCHEMBL22231994 0.82 KMT2A (0.39) KDM4EALDH1A1HPGDMKNK1CDK5
SCHEMBL22231932 0.79 MEN1 (0.50) KDM4EALDH1A1CDK5KMT2ARAB9A
SCHEMBL29454061 0.79 MEN1 (0.50) KDM4EALDH1A1CDK5KMT2ARAB9A
SCHEMBL11900501 0.79 ALDH1A1 (0.45) KDM4EALDH1A1HPGDCDK8GSK3A
SCHEMBL28646747 0.79 NUDT1 (0.40) KDM4ECDK8GSK3AGSK3BCDK9
SCHEMBL12589876 0.75 MKNK1 (0.42) KDM4EALDH1A1HPGDMKNK1KMT2A
SCHEMBL31723219 0.75 PLAU (0.37) ALDH1A1DYRK1BKMT2ARAB9ANPC1
SCHEMBL22232534 0.75 PLAU (0.37) ALDH1A1DYRK1BKMT2ARAB9ANPC1
SCHEMBL28646744 0.75 MKNK1 (0.35) KDM4EALDH1A1HPGDMKNK1CDK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed